In The ShowEdit
He strongly dislikes Providence, stating that he does not like them meddling with his plans. He does not like the fact that people see Providence as "saviors", as Van Kleiss sees himself as the true "savior". He purposely did not announce his arrival in New York City or about his diplomatic immunity, so that Providence would attack him and his henchmen, just for the purpose of humiliating them. Furthermore, when Rex asked Van Kleiss why he always tries to destroy a cure, Van Kleiss responded that he lives off of nanites and what Providence calls a "cure", he calls "death".